Click the available organ until it's received enough adrenaline, and another organ is available.

Click the eye, then quickly click the heart until the liver is available, then quickly click the liver until you're done. The eye requires 1 click, the heart requires 6 (but it's a little twitchy), and the liver requires 24. Of course, it's best to just click an organ repeatedly until the next one is ready.

Click the hemoglobin when it's inside the lungs to make it carry oxygen. When hemoglobin carrying oxygen (it'll be marked with blue dot, lighter than the hemoglobin itself) arrives at the muscles, click it again to release the oxygen. When hemoglobin is in the lungs or muscles, it glows light blue regardless of whether it's carrying oxygen.

Try to pay attention to both muscles and lungs, but if you need to focus on one more, then concentrate on the lungs first. When enough hemoglobin is carrying oxygen, work on getting it to the muscles. Once oxygen has been brought to the lungs 7 times, you're done.

Click the heart while the moving line is in the center space. If you've done it correctly, the blood around the heart will spin.

Don't worry about failure: missing a click or clicking incorrectly won't set you back. You need about 15-30 correct clicks to proceed (sometimes it doesn't register successive clicks, so I couldn't get an exact count). It appears that you don't need to completely fill the bar in order to proceed, as long as it's most of the way there.

Click a highlighted blood vessel to constrict it. A blood vessel only stays highlighted for a limited time.

Success or failure depends on the amount of blood Fred loses, not on whether you click every blood vessel, so just click as many as you can (if it's too quick for you, try focusing on one side). If the timer runs out and you haven't killed Fred yet, you've succeeded.

Click platelets (purple, circular) to build a plug, then click clotting factors (blue, spiky) to create a clot, then click fibroblasts (pink, flat and pointed) to form a permanent scar.

Platelets and clotting factors float through the bloodstream, and fibroblasts stay in place in Fred's skin. You need 6 platelets, 7 clotting factors, and 13 fibroblasts. However, success or failure is measured by Fred's blood loss, and building the platelet plug stops the blood loss completely. As long as you get the platelets finished in time, you'll progress.

Click the circle on the edge of each nerve to grow it back into place. As time goes by, the circles shrink, representing the life of the nerve. If a circle shrinks down to nothing, the nerve dies and you fail the minigame, even if there's still time left on the clock. Clicking a nerve to grow it brings its circle back to full size.

Don't just concentrate on one nerve at a time, alternate between all of them. Each nerve takes 10 clicks, and you need three finished nerves when the clock runs out to succeed. If one nerve dies, that's not an automatic loss.

Click the cilia on each side of Fred's throat (they look like little hairs) to shuffle the bacteria out. If they fall off the screen, you'll fail the stage.

The cilia move slowly, but you have a lot of time. Since they can only push the bacteria up when they're facing somewhat downward, it helps to alternate between sides.

Click on bacteria to destroy them and collect the fragments. Then, click the lymph node to deposit the fragments.

As long as you collect enough fragments, you don't need to destroy every bacterium. You need fragments from 12 bacteria before you can drop them off at the lymph node. Ignore the red blood cells-- they don't do anything.

Click the glowing white orbs to release antibodies to destroy the bacteria before they reach the cells at the screen. The illuminated area from each orb shows its range. If the infection spreads to all of the cells, you'll fail the stage.

You don't need to get every single bacterium, and sometimes you can't. All you need to do is survive until the end of the stage. If you can't get everything, go for the large groups and don't worry about the stragglers.

Click an organ when a protein floats directly above it to send that organ energy. If any organ loses its entire energy bar, you'll fail the stage.

Focus on getting energy to the organs on the right of the screen. Try to build up a bit of a buffer. Proteins float by pretty regularly, so when the organs on the left are in danger, you'll almost always be able to get them energy quickly. Don't worry about filling up the bars- you'll succeed as long as all the organs are still around when the clock runs out.

Click the fat (pinkish purple, three oval shapes in a row), carbs (yellow, sort of shaped like a fruit gusher), and proteins (dark purple, spirally) as they come down through the digestive system. Nutrients are clickable while in the stomach, and are absorbed automatically while in the intestine. Absorb enough of everything to continue.

You need 4 of each nutrient type to proceed. Just try to click everything as it comes through at the top of the digestive system- if time's running out and you're only missing one nutrient, you can look for it, but it's really easier to just go for everything that comes through.

Click the pancreas to release insulin (which moves the bottom meter to the left by a little) and the liver to release glucose (which moves the bottom meter to the right by a lot). The bottom meter slowly moves to the left as time passes. When it's in the "sweet spot" in the middle, glucose is delivered to Fred's body and the meter on the right fills up. Fill up that right meter to finish the minigame (and the game proper).

Click the pancreas when the bottom meter is too far to the right until it's close to the "sweet spot", then let it pass through. Once the meter has left the sweet spot, click the liver once. Then repeat. You can still win if the meter on the right isn't entirely full, so just give it your best.